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Beta-amyloid deposit of human AB42 in Drosophila’s olfactory neuron. Nuclei in blue (DAPI). Beta-amyloid in green (α6E10 coupled to GFP).


Electrophysiological recordings in Drosophila melanogaster antenna in response to pulses of smell. On the left, a fixed, whole and alive Drosophila with the recording electrode located on the antenna. On the right, trace of responses observed in single neurons SSR Single Sensillum Recording (in blue) compared to a pulse of smell (in red).


Alino Martínez

Immunofluorescence on a section of the mouse hippocampus. The photography shows the cell nuclei (blue), calretinin- expressing cells (green) and the pathological protein for Parkinson's disease, named α-synuclein (red). Memory loss and cognitive problems are part of the extensive symptoms of this neurodegenerative disease, therefore the importance of the image lies in the possibility of observing how the hippocampus is affected in certain stages. LSM710 Zeiss confocal microscope.

De Carlos

Example of an injection made with this equipment. The fist picture shows the injection site in the telencephalic rostral Medial Wall (MMRT), with the fluorescent tracer (green) CFDA, in a counter-stained coronal section of blue with bisbenzimide. The following pictures show sequential images of the rostro-caudal axis of the brain, where labeled cells can be seen (in green) settled on the subplate cortical layer, highlighting that they have been generated at the site of injection (MMRT). These sections were also counterstained in blue to facilitate the marking location.


Immunocytochemistry performed in primary culture of rat hippocampal neurons at 12 DIV. In green is observed the neuronal structure marked with an antibody against the microtubule-associated protein MAP2. In red is observed GSK3beta fraction S9 phosphorylated at serine that marks both neurons and astrocytes.


Morphology and connectivity of olfactory bulb interneurons.


The picture A shows a granule neuron of the mouse olfactory bulb labeled with GFP that allows visualization of the dendritic tree with abundant spines.

The picture B shows a hippocampal neuron in cell culture immunostained with antibodies against MAP2ab (dendrites; blue) and synaptophysin that mark presynaptic buttons.


Clonal dispersión of cells in the mouse olfactory bulb (P15) after electroporation in utero (E14) of the plasmid mixture  StarTrack-Ubc in the SVZ.

Cells of the adult mouse hippocampal dentate gyrus modified to express GFP (green cells).

Development of a baseline correction for GC-MS data



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